With 17 available rotor options, the Z326 defines the term "universal". Swinging bucket rotors and high speed angled rotors are available to accept tubes from 0.2 ml up to 85 ml, making the Z326 series suitable for nearly any laboratory application. Despite an impressive capacity of up to 4 x 100 ml (or 6 x 85 ml), the Z326 is surprisingly compact with the standard air-cooled model with a width of just over 15 inches.

Advanced microprocessor controls allow for instant rotor identification, which automatically converts the rotational speed to the relevant g-force (rcf), preventing the user from setting a speed above the capabilities of the installed rotor. In addition to retrieving saved programs, the easy to use front panel can adjust accel/decel rates, and change the end of run alarm tone.